Pharmacognosy & Phytochemistry

The focus area of department isIntegrative taxonomy, Structural genomics, Genetic engineering, RNA interference, Pharmacognosy and Phytochemistry.

Research Activities

Natural products

  • Authentication of herbal drugs
  • Standardization of herbal drugs and formulations
  • Marker compound analysis
  • In vitro and in vivo efficacy of herbal drugs and extracts and formulations

Plant Biotechnology

  • Design and development of protocols for micropropagation, shoot regeneration, root regeneration, callus culture and cell suspension culture
  • Genetic engineering for production of heterologous proteins
  • DNA barcoding and molecular markers for quality assessment
  • RNA interference for trait improvement

Animal Biotechnology

  • RNA interference has been used in cancer therapeuticsto downregulate overexpressing oncogenes mediating cancer angiogenesis, apoptosis and metastasis.
  • List of some medicinal plants investigated

    • Adhatoda vasica
    • Holarrhena antidysenterica
    • Bacopa monnieri
    • Nicotiana tabacum
    • Balanitis roxburghii
    • Phyllanthus amarus
    • Boerhaavia diffusa
    • Polyalthia longifolia
    • Catharanthus roseus
    • Saraca asoca
    • Cassia senna
    • Sida cordifolia
    • Clerodendrum inerme
    • Terminalia alata
    • Convolvulus microphyllus
    • Terminalia arjuna
    • Evolvulus alsinoides
    • Terminalia bellerica
    • Terminalia chebula
    • Vitex negundo

Industrial Services

  • Identification and authentication of plant/plant material.
  • Macroscopic andmicroscopic examination of herbal drugs and polyherbal formulations.
  • Development of quantitative standards viz. extractive values, ash values, fixed oil content, loss on drying.
  • Development of phytochemical profiles (fingerprint) using HPTLC,/HPLC/GC/GLC depending upon the nature of the sample.
  • Isolation of marker compounds and estimation/quantification using various techniques.
  • Microbial load testing
  • Authentication of herbal raw material using DNA fingerprint profile (molecular markers).
  • Development of tissue cultures of medicinally and economically important plants and consultation.
  • Library of reference standards

Academic Services

  • Dissertation
  • Hand-on-Training Workshop and Tailor-made programme

Lab Group Photograph

Instruments

Ph. D. Students

Mrs. Sonal Sharma

RESEARCH AREA : Development of DNA based marker for authentication and unequivocal identification of medicinal plants with special to adulterants.

Mr. Manish Patel

RESEARCH AREA : Development and characterization of in vitro cell competition model in human cancer cell lines and identification of microRNAs involved in cell competition.

Ms. Heta Shah

RESEARCH AREA : Characterization of proximal tubule cell lines and its application in drug induced nephrotoxicity prediction.

Alumni

Dr. Anshu Shrivastava
Scientist B, PERD, Centre

Dr. Astha Varma
Mumbai
Dr. Indira Purohit
Dr. Sheetal Yadav
IIT, Kharagpur
Dr. Poojadevi Sharma
NCL, Pune